Clog Resistant Spray Devices
When compared to conventional designs of nanospray sources, which typically have a long, narrow bore tube of a few microns in diameter, and are made of materials such as silica, the polypropylene nozzle, with its relatively large orifice and conical channel, are far less likely to clog even by diluted but unfiltered serum or plasma samples, yet the hydrophobic plastic material construction of the nozzle allows nanospray at very low flow rate (<50nL/min).

Microspray and Nanospray in a single spray emitter
Nanospray and microspray provide high ionization efficiency and consumes mere nanoliters of samples. Low flow rate (under 50 nL/min) nanospray, in addition to the obvious advantage of conserving scarce samples, offers desirable performance advantages such as higher sensitivity and higher tolerance for salts in the samples. However, many LC methods prefer flow rates at 1 µL/min or higher. Both the nanospray nozzles and the polymeric polytip can be used for the entire range of these flow rates. For flow rates in the microspray range, i.e. > 1 µL/min, a concentric flow of nitrogen gas ensures effective ionization of the eluates.
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ASMS - May 23-27, 2010 - Booth #100 - Presentation and Posters Monday & Tuesday, May 24 & 25, 10:30am - 2:30pm
Phoenix S&T introduces the µAutoNano LC and column heaters
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