The pneu-Nimbus operation demo Watch Now

Butterfly heater at ETH Zurich Learn More

Installation video of the Nimbus system on an OrbiTrap MS Watch Now

Providing robust solutions to proteomic mass spec research challenges
Phoenix S&T Technology
Phoenix S&T core technology is based on the miniaturization and integration of laboratory equipment with concomitant enhancement in performance in proteins and small molecules characterizations. The product that exemplifies this approach is a patented three-dimensional nanospray nozzle chip micromolded with polypropylene for handling nanoliters quantities of sample, high sensitivity mass spectrometer detection, and seamless integration into customers' existing mass spectrometers.

The nanospray nozzles are conical structures 0.5 mm to 1.5 mm in height. The orifice of the nozzle has a 20+/- 3 Ám i.d, and the outside diameter is 50 Ám. These dramatically different dimensions in 3-D are manufactured in a single step in a factory.

Our products for nanospray LC-MS and microspray LC-MS applications focus on a polymeric spray tip integrated with the separation column to create a simple, non-clogging, zero dead volume solution for practitioners in proteomics and metalobomics.
Spray Click for larger image

The high performance, micromolded nanospray nozzles, and the polytips are deployed by a family of automated nanospray and microspray sources for every need. These sources increase the robustness, throughput, and sensitivity of nano-LC/MS, micro-LC/MS, and CHIP-Di/MS applications. Innovations such as: programmable high voltage for optimizing multiply charged compounds, dual column switching to eliminate wait time before the MS for column equilibration, and active spray controls based on current feedback to restore lost spray, all set us apart from other nanospray sources in functionality and performance.

Our products in the pipeline include high throughput multiplexed LC-MS with increased sensitivity, and two dimensional microfluidic plastic devices packed with nanoparticles for ultrahigh resolution separations and high efficiency mass spectrometry detection. This product development is partially supported by an NIH SBIR Phase 2 grant.
© Phoenix S&T. All Rights Reserved.

"I'm very satisfied those (eFrit) columns. Resin was very efficiently packed without any stopping,"
-Lee Hyoung-Joo, Yonsei Proteomix Research Center, Seoul, Korea

"The carryover issue is definitely gone; I keep the temp at 40C, and it only takes one blank run to get rid of carryovers. I like the column heater."
-Eric Chan, PhD, Constellation Pharmaceuticals

"The µAutoNano dual-column source has in effect added an extra OrbiTrap and nanoflow pump to my lab without extra space and maintenance, and the column heater has allowed us to run analyses on 29 cm long Halo columns without a uPLC.  This has represented a huge cost savings for the lab."
-Stephen Master, MD, Ph.D., University of Pennsylvania School of Medicine

"Phoenix S&T provides great products and customer care for nanoLC-MS. I use their nanospray source for the Thermo LTQ and TSQ MS."
Kwasi Mawuenyega, Ph.D., Washington University

Play MovieVideos
The Nimbus dual-column source in action

Dual-column Spray: Automated Column Switching
Live video shows automatic column switching. A new column is positioned, the spray purges and clears for virtually uninterrupted electrospray.
  • SureSpray(TM) plastic nozzle spray: non-clogging, robust spray

    Jun 4-Jun 8, 2017 - 65th ASMS Conference on Mass Spectrometry: Indianapolis, IN.

    Visit Phoenix S&T at Booth #520

    and see the new robust non-clogging, ultra-stable micropray system for the Thermo Easy-spray source! Also the pneu-Nimbus and Easy-Spray compatible column heater!

  • Come back soon to see our newly re-designed website with on-line shopping of some of our consumable products!

    More product information or pricing, please click here.

    t. (610) 876.6081
    f. (610) 876.6084